East China University of Science and Technology (EUST) is one of the key universities under the "211 Project" and the "985 Project Advantageous Discipline Innovation Platform". The university has 15 professional colleges and 67 undergraduate majors in 11 disciplines including science, engineering, agriculture, medicine, economics, management, literature, law, art, philosophy and education.

The university has 8 national research bases, 23 provincial and ministerial research bases, 2 international cooperative research bases, 55 university-level research institutes (centers), and the National University Science and Technology Park, which is one of the first 6 universities in China to establish the National Technology Transfer Center. There are 2 national experimental teaching demonstration centers, 2 national virtual simulation experimental teaching centers, 3 Shanghai experimental teaching demonstration centers, 12 national characteristic majors, 5 national engineering practice education centers, a demonstration experimental zone for the cultivation of entrepreneurship talents, and an experimental base for innovation and entrepreneurship education in Shanghai universities.

 

1、SE pulverized coal pressurized gasification technology

In order to meet the urgent need of clean and efficient gasification of high ash melting point and high ash content of poor quality coal in China, the project has spent nearly 20 years on research and development. Based on the research of high temperature and high pressure dense particle dispersion, turbulent multiphase reaction flow field control and slag phase change heat transfer, the key equipment and complete sets of technology of SE pulverized coal pressurized gasification have been invented, and a major breakthrough of independent intellectual property rights of pulverized coal pressurized gasification technology has been realized. The main innovations of this technology are as follows.

(1) Long-life, all-in-one powder coal gasification nozzle.

(2) High performance membrane water-cooled wall liner.

(3) Applicable to gasifier of poor quality coal with high ash melting point and high ash content.

The SE pulverized coal pressurized gasification technology with the above-mentioned nozzle and water-cooled wall gasifier as the core equipment has been successfully applied in the 1.3 billion RMB coal gasification hydrogen plant of Sinopec Yangzi Petrochemical Co. The company's products include feedstock gas, hydrogen production, industrial gas, reduced iron production, fuel cells and IGCC power generation.

 

2. Green bio-manufacturing and high-value applications of amino-oligosaccharides

Amino sugars are the only cationic sugars in nature widely used in food, medicine, agriculture and other fields, with rich uses and important physiological activities, and great economic and social value.

A strain of N-Acetylglucosamine (NAG) metabolism engineering bacterium was constructed with high yield, using glucose to synthesize NAG, with high fermentation level of 115g-120g/L in 50m3 fermenter; a strain with high enzyme activity and specific catalytic hydrolysis of glucosamine was screened and constructed, with fermentative enzyme activity of 200u/ml, which was 5 times higher than the reported chitosan enzyme activity and optimized. The first large-scale production of DP6-8 glycans was achieved by using a synergistic hydrolysis technique with a non-specific enzyme, with the molecular weight of the hydrolysate concentrated in the range of 350-1200 Da. Based on the constructed specific enzyme with optimum reaction pH 5-7, the enzymatic coupled continuous chromatography technique was established and neutral oligosaccharides in the pH 6-8 range were prepared on a large scale for the first time; several technical problems on the stability and application of oligosaccharides were overcome, and the stability of oligosaccharides and the stability of complexation between oligosaccharides and chemical fungicides were solved.

We have developed a number of high-end oligosaccharide raw materials, functional foods, health care products, biopesticides and biofertilizers that have been industrially promoted.

 

3、Green long-lasting corrosion coating

In this project, aniline and its derivative monomers were oxidatively co-polymerized in acidic aqueous solution, and surface-modified polyaniline was prepared by adding surfactants with HLB values in the range of 10-13 at the beginning of the reaction, which solved the problem of poor dispersion of existing polyaniline in conventional solvents. Using the interfacial polymerization method, we developed the preparation technology of easily dispersed conductive polyaniline nanoparticles, successfully solved the problem of polyaniline processing in aqueous system, and developed polyaniline epoxy primer, polyaniline polyurethane topcoat and water-based polyaniline anti-corrosion paint, etc. The relevant results declared three national invention patents, of which two were authorized (patent no. ZL03151472.3. ZL201110195910.6), the coating performance not only meets the technical indexes of the Eleventh Five-Year Project Guide of the National Defense Science, Technology and Industry Commission (JPPT-115-423, anticorrosive coating for more than 10 years), but also has outstanding weathering resistance and aging performance.

After the project is applied, its preparation process will be low energy consumption and low environmental pollution, which is in line with Shanghai's industrial policy and will become a new growth point for economic development. The polyaniline anti-corrosion coating can be used for the anti-corrosion protection of ships, containers, port terminals, bridges, oil pipelines and storage tanks, nuclear power plants and other heavy-corrosion fields. In addition, it can also be used for the corrosion protection of the outer shell of military equipment such as warships, submarines, tanks and missile launchers. This polyaniline anti-corrosion coating replaces the existing anti-corrosion coating and has a positive impact on marine environmental protection.

 

4. Fully degradable low-carbon biocomposites

(1) Using non-food starch as the raw material, we investigated the preparation technology of straight-chain starch, the interfacial capacitance enhancement technology of starch-based plastic, and optimized the preparation, modification, and processing processes of the material as well as the low-cost and high-value preparation process of starch-based fully degradable plastic. Carboxylated polypropylene glycol (PPG) graft-modified starch was prepared as a compatibilizer to improve the compatibility of PLA/starch blended materials, so that the blended materials have good mechanical and processing properties. The Vicat softening temperature of the blends was improved by blending acetate starch with high optical purity L-polylactic acid (PLLA) and D-polylactic acid (PDLA), respectively, which provides a new way to improve the heat resistance of starch plastic alloys. The PVA/PLA/SA blends were modified with glycidyl methacrylate grafted POE (G-POE) as a toughening agent, which improved the impact strength of the blends and the water resistance of the materials. The injection molding, blister molding and blown film products of starch-based degradable plastics have been developed.

(2) Biomass matrix composites filled with bamboo pulp fibers were prepared by using the polymer polybutylene succinate (PBS) as the resin matrix, and the effects of the content of bamboo pulp fibers on the mechanical properties, crystallization properties and melting behavior of the biomass matrix composites were investigated, and the relationship between their structure and properties was analyzed. Among them, the biomass materials such as bamboo powder, wood powder and cellulose and the biodegradable polymers PLA and PBS belong to the fully biodegradable products, which are suitable for applications such as disposable products.

3）Research the new process of modified starch series products, conduct esterification, etherification, oxidation, enzymatic digestion, grafting five types of modified starch process research, establish the wet denaturation of the main, combined with semi-dry, dry, microwave method for composite denaturation production of new technology, environmental coatings, wallpaper glue, seeds, water retention coating and fresh coating application research and development of new products.

 

5、Chemical clean production and key technologies for enhanced pollutant removal and recovery

This project is in the field of clean production and resource recovery technology. For the recovery of clean production and enhanced removal of pollutants in chemical production, a new process for the separation of amidation reaction liquid in the toluene process of caprolactam production is invented; for the enhanced removal of pollutants from waste liquids, a new idea of enhanced extraction and removal of unsteady flow is proposed, and the first centrifugal enhanced extraction and removal of caprolactam-containing residuals and enhanced removal of sodium ions from gasoline are invented. For the removal of high-density oils, a new method of "oil washing" was proposed and a new process of enhanced oil removal from electrically desalinated wastewater was invented. Two types of centrifugal extraction and separation equipment for rapid separation and enhanced extraction and separation were successfully developed.

The above-mentioned set of technologies has built three types of chemical process clean production and resource recovery technology demonstration devices, including rapid separation of heat-sensitive materials, enhanced extraction to remove pollutants and enhanced removal of high-viscosity, high-density dirt oil. The technology has been applied in 8 sets of engineering projects. The centrifugal enhanced separation technology of amidation reaction liquid in caprolactam process is at the leading level in China, and the centrifugal enhanced extraction and removal technology of waste liquid containing caprolactam is the first of its kind at home and abroad.

 

6. Enzymatically asymmetric synthesis of the chiral intermediate (R)-2-hydroxy-4-phenylbutyric acid ethyl ester of puromycin.

This project developed a biotechnology for the enzymatic asymmetric reduction of ethyl 2-oxo-4-phenylbutyrate to prepare the key chiral intermediate (R)-2-hydroxy-4-phenylbutyrate for a variety of Puri drugs. The technology is easy to scale up, mild reaction (30oC, pH 6.0), high optical purity of the product (>99%), 85% yield, and no need to add expensive coenzyme regeneration system. The implementation of the project will save energy and reduce emissions by 20-30%, reduce production costs by more than 20%, and increase product yield by 15%, showing that the technology has good prospects for industrial application.

 

7. Chemical and enzymatic synthesis of L-carnitine.

This project developed a technique for the enzymatic asymmetric reduction of ethyl 4-chloroacetoacetate to prepare the key chiral intermediate of L-carnitine drug, ethyl (R)-4-chloro-3-hydroxybutyrate. The advantages of this technique: the mild reaction conditions (30oC, pH 6.5), short synthetic route, and low energy consumption make it technically promising. In addition, the substrate concentration is above 100g/L, the product yield is high (above 85%), and the optical purity of the product is good (above 99%). Therefore, the product is of high quality and has a good market prospect.

Technical innovation: 1) The reaction conditions of this synthesis route are mild (30oC, pH 6.5), short synthesis route, low energy consumption, which has good application prospect technically.2) The substrate concentration is above 100 g/L, the product yield is high (above 85%), and the optical purity of the product is good (above 99%).

 

8、Development and industrialization of intelligent fire-fighting Internet of Things sensing products.

The project utilizes Internet of Things technology to develop fire facility status monitoring equipment to monitor real-time fire pipeline pressure, flow, temperature, smoke level, fire hydrant, fire extinguisher and fire channel images, expiration date and maintenance information; developed fire power monitoring equipment and nodes, central controller for fire power, repeaters and other products to effectively monitor the fire power; developed user information transmission module. It can get the status operation information and alarm information of the present firefighting system and transmit it to the remote cloud service platform according to the relevant standards. The company has developed an intelligent fire-fighting specification based on the Internet of Things, applied for 12 invention patents (8 authorized), and promoted the implementation in Hunan Mass Media Building, Changsha Economic Development Zone and other units, which has achieved good economic communication and social benefits.

It can be applied to fire fighting facilities in large buildings, entertainment venues, science and technology museums, museums and other important public places remotely.

 

      Contact details

Contact：021-55230656

E-mail: info@gaoxiaotech.com

Website address: www.gaoxiaotech.com